Obtusifolin (anthraquinone)
obtusifolin
CAS: 477-85-0
Molecular Formula: C16H12O5
Obtusifolin (anthraquinone) - Names and Identifiers
Obtusifolin (anthraquinone) - Physico-chemical Properties
| Molecular Formula | C16H12O5 |
| Molar Mass | 284.26 |
| Density | 1.448±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 242-243℃ |
| Boling Point | 528.0±50.0 °C(Predicted) |
| Solubility | Soluble in DMSO, methanol and other solutions. |
| Appearance | Yellow powder |
| pKa | 6.60±0.20(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD18452296 |
| Physical and Chemical Properties | Orange-yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from cassia seed. |
| In vitro study | Obtusifolin (1, 10, 100 μM) inhibits MUC5AC gene expression induced by EGF, PMA, or TNF-α in NCI-H292 cells. |
Obtusifolin (anthraquinone) - Reference
| Reference Show more | 1. Xie, Li, et al. "Development of an UHPLC-MS/MS method for comparative pharmacokinetics of nine anthraquinones in rats and application to dosage conversion between different Semen Cassiae forms." Journal of pharmaceutical and biomedical analysis 174 (2019): 2. [IF=3.935] Li Xie et al."Development of an UHPLC-MS/MS method for comparative pharmacokinetics of nine anthraquinones in rats and application to dosage conversion between different Semen Cassiae forms."J Pharmaceut Biomed. 2019 Sep;174:696 |
Obtusifolin (anthraquinone) - Introduction
obtusifolin, also known as White Cassia, is a natural chemical whose chemical structure is mainly composed of homo-tyrosine. It is a white crystalline powder, tasteless and odorless, soluble in water and ethanol.
obtusifolin is often used in whitening skin care products, with obvious whitening effect. It can inhibit the production of melanin, reduce pigmentation, improve uneven skin tone. In addition, obtusifolin also has antioxidant properties, can scavenge free radicals, slow down the aging process of the skin.
There are two main methods for preparing obtusifolin. One is to extract the desired compounds from natural materials through chemical synthesis. The other is through fermentation, the use of specific microbial synthesis products.
Although obtusifolin is widely used in beauty and skin care and is considered a relatively safe chemical substance, it is still necessary to pay attention to the safety of its use. Before using obtusifolin, it is recommended to conduct an allergy test to exclude the risk of allergic reactions. In addition, avoid prolonged exposure to the sun to avoid causing photosensitive reactions. If you find symptoms, you should stop using it in time and consult a professional.
obtusifolin is often used in whitening skin care products, with obvious whitening effect. It can inhibit the production of melanin, reduce pigmentation, improve uneven skin tone. In addition, obtusifolin also has antioxidant properties, can scavenge free radicals, slow down the aging process of the skin.
There are two main methods for preparing obtusifolin. One is to extract the desired compounds from natural materials through chemical synthesis. The other is through fermentation, the use of specific microbial synthesis products.
Although obtusifolin is widely used in beauty and skin care and is considered a relatively safe chemical substance, it is still necessary to pay attention to the safety of its use. Before using obtusifolin, it is recommended to conduct an allergy test to exclude the risk of allergic reactions. In addition, avoid prolonged exposure to the sun to avoid causing photosensitive reactions. If you find symptoms, you should stop using it in time and consult a professional.
Last Update：2024-04-09 20:52:54
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